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Cleavage of galectin-3 by matrix metalloproteases induces angiogenesis in breast cancer

Galectin-3 cleavage is related to progression of human breast and prostate cancer and is partly responsible for tumor growth, angiogenesis and apoptosis resistance in mouse models. A functional polymorphism in galectin-3 gene, determining its susceptibility to cleavage by matrix metalloproteinases (...

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Bibliografische gegevens
Hoofdauteurs: Nangia-Makker, Pratima, Wang, Yi, Raz, Tirza, Tait, Larry, Balan, Vitaly, Hogan, Victor, Raz, Avraham
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334857/
https://ncbi.nlm.nih.gov/pubmed/20162566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.25254
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