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Targeting the Insulin Growth Factor Receptor 1
The IGF axis is a tightly controlled endocrine system that regulates cell growth and development, known to have an important function in cancer biology. IGF1 and IGF2 can promote cancer growth in a GH-independent manner both through paracrine and autocrine secretion and can also confer resistance to...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3334849/ https://ncbi.nlm.nih.gov/pubmed/22520978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hoc.2012.01.004 |
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