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Antibiotics in critically ill patients: a systematic review of the pharmacokinetics of β-lactams

INTRODUCTION: Several reports have shown marked heterogeneity of antibiotic pharmacokinetics (PK) in patients admitted to ICUs, which might potentially affect outcomes. Therefore, the pharmacodynamic (PD) parameter of the efficacy of β-lactam antibiotics, that is, the time that its concentration is...

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Detalhes bibliográficos
Main Authors: Gonçalves-Pereira, Joao, Póvoa, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334750/
https://ncbi.nlm.nih.gov/pubmed/21914174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc10441
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