The endogenous proteoglycan-degrading enzyme ADAMTS-4 promotes functional recovery after spinal cord injury

BACKGROUND: Chondroitin sulfate proteoglycans are major inhibitory molecules for neural plasticity under both physiological and pathological conditions. The chondroitin sulfate degrading enzyme chondroitinase ABC promotes functional recovery after spinal cord injury, and restores experience-dependen...

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Main Authors: Tauchi, Ryoji, Imagama, Shiro, Natori, Takamitsu, Ohgomori, Tomohiro, Muramoto, Akio, Shinjo, Ryuichi, Matsuyama, Yukihiro, Ishiguro, Naoki, Kadomatsu, Kenji
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334708/
https://ncbi.nlm.nih.gov/pubmed/22420304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-53
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