Notochordal cells protect nucleus pulposus cells from degradation and apoptosis: implications for the mechanisms of intervertebral disc degeneration

INTRODUCTION: The relative resistance of non-chondrodystrophic (NCD) canines to degenerative disc disease (DDD) may be due to a combination of anabolic and anti-catabolic factors secreted by notochordal cells within the intervertebral disc (IVD) nucleus pulposus (NP). Factors known to induce DDD inc...

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Autors principals: Erwin, W Mark, Islam, Diana, Inman, Robert D, Fehlings, Michael G, Tsui, Florence WL
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334668/
https://ncbi.nlm.nih.gov/pubmed/22206702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3548
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