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Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis

INTRODUCTION: Osteoarthritis (OA) is a complex, multifactorial joint disease affecting both the cartilage and the subchondral bone. Animal models of OA aid in the understanding of the pathogenesis of OA and testing suitable drugs for OA treatment. In this study we characterized the temporal changes...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mohan, Geetha, Perilli, Egon, Kuliwaba, Julia S, Humphries, Julia M, Parkinson, Ian H, Fazzalari, Nicola L
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334663/
https://ncbi.nlm.nih.gov/pubmed/22185204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3543
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