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Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis

INTRODUCTION: Osteoarthritis (OA) is a complex, multifactorial joint disease affecting both the cartilage and the subchondral bone. Animal models of OA aid in the understanding of the pathogenesis of OA and testing suitable drugs for OA treatment. In this study we characterized the temporal changes...

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Библиографические подробности
Главные авторы: Mohan, Geetha, Perilli, Egon, Kuliwaba, Julia S, Humphries, Julia M, Parkinson, Ian H, Fazzalari, Nicola L
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334663/
https://ncbi.nlm.nih.gov/pubmed/22185204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3543
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