Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus

INTRODUCTION: Inherited deficiencies of several complement components strongly predispose to systemic lupus erythematosus (SLE) while deficiencies of complement inhibitors are found in kidney diseases such as atypical hemolytic uremic syndrome (aHUS). METHODS: The exons of complement inhibitor genes...

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Main Authors: Jönsen, Andreas, Nilsson, Sara C, Ahlqvist, Emma, Svenungsson, Elisabet, Gunnarsson, Iva, Eriksson, Karin G, Bengtsson, Anders, Zickert, Agneta, Eloranta, Maija-Leena, Truedsson, Lennart, Rönnblom, Lars, Nordmark, Gunnel, Sturfelt, Gunnar, Blom, Anna M
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2011
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334659/
https://ncbi.nlm.nih.gov/pubmed/22171659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar3539
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