Accurate proteome-wide protein quantification from high-resolution (15)N mass spectra

In quantitative mass spectrometry-based proteomics, the metabolic incorporation of a single source of (15)N-labeled nitrogen has many advantages over using stable isotope-labeled amino acids. However, the lack of a robust computational framework for analyzing the resulting spectra has impeded wide u...

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Autores principales: Khan, Zia, Amini, Sasan, Bloom, Joshua S, Ruse, Cristian, Caudy, Amy A, Kruglyak, Leonid, Singh, Mona, Perlman, David H, Tavazoie, Saeed
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Method
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334617/
https://ncbi.nlm.nih.gov/pubmed/22182234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-12-r122
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