Implications for health and disease in the genetic signature of the Ashkenazi Jewish population

BACKGROUND: Relatively small, reproductively isolated populations with reduced genetic diversity may have advantages for genomewide association mapping in disease genetics. The Ashkenazi Jewish population represents a unique population for study based on its recent (< 1,000 year) history of a lim...

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Hoofdauteurs: Guha, Saurav, Rosenfeld, Jeffrey A, Malhotra, Anil K, Lee, Annette T, Gregersen, Peter K, Kane, John M, Pe'er, Itsik, Darvasi, Ariel, Lencz, Todd
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2012
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334583/
https://ncbi.nlm.nih.gov/pubmed/22277159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2012-13-1-r2
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