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Predicting responses to sunitinib using single nucleotide polymorphisms: Progress and recommendations for future trials

Targeted therapy with tyrosine kinase inhibitors has led to a substantial improvement in the standard of care for patients with advanced or metastatic clear cell renal cell carcinoma. Because the mechanism of action, metabolism and transport of tyrosine kinase inhibitors can affect outcome and toxic...

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Autors principals: Ganapathi, Ram N, Bukowski, Ronald M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334544/
https://ncbi.nlm.nih.gov/pubmed/22212486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm295
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