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Relationships Between Expression of Apolipoprotein E and β-Amyloid Precursor Protein Are Altered in Proximity to Alzheimer β-Amyloid Plaques: Potential Explanations from Cell Culture Studies

Theories about the initiation and progression of Alzheimer disease (AD) often consider potential roles played by elevations of β-amyloid precursor protein (βAPP). Since it is the source of amyloid β-peptide (Aβ), βAPP may simply contribute more pathogenic stimulus when elevated; some analyses have,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Barger, Steven W., Mark DeWall, K., Liu, Ling, Mrak, Robert E., Griffin, W. Sue T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334532/
https://ncbi.nlm.nih.gov/pubmed/18648325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e318180ec47
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