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Susceptibility to a parkinsonian toxin varies during primate development

Symptoms of Parkinson’s disease typically emerge later in life when loss of nigrostriatal dopamine neuron function exceeds the threshold of compensatory mechanisms in the basal ganglia. Although nigrostriatal dopamine neurons are lost during aging, in Parkinson’s disease other detrimental factors mu...

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Detalhes bibliográficos
Main Authors: Morrow, B.A., Roth, R.H., Redmond, D.E., Diano, S., Elsworth, J.D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334464/
https://ncbi.nlm.nih.gov/pubmed/22366325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.02.005
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