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An Embryonic Stem Cell Based System for Rapid Analysis of Transcriptional Enhancers

With the growing use of genome-wide screens for cis-regulatory elements, there is a pressing need for platforms that enable fast and cost-effective experimental validation of identified hits in relevant developmental and tissue contexts. Here, we describe a murine embryonic stem cell (ESC) based sys...

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Main Authors: Tsanov, Kaloyan M., Nishi, Yuichi, Peterson, Kevin A., Liu, Jing, Baetscher, Manfred, McMahon, Andrew P.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334447/
https://ncbi.nlm.nih.gov/pubmed/22083581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20820
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