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Prevention of Paclitaxel-Induced Neuropathy Through Activation of the Central Cannabinoid Type 2 Receptor System

BACKGROUND: Peripheral neuropathy is a major dose-limiting toxicity of chemotherapy, especially after multiple courses of paclitaxel. The development of paclitaxel-induced neuropathy is associated with the activation of microglia followed by the activation and proliferation of astrocytes, and the ex...

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Detalhes bibliográficos
Main Authors: Naguib, Mohamed, Xu, Jijun J., Diaz, Philippe, Brown, David L., Cogdell, David, Bie, Bihua, Hu, Jianhua, Craig, Suzanne, Hittelman, Walter N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334436/
https://ncbi.nlm.nih.gov/pubmed/22392969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e31824b0191
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