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Pharmacologic ER Stress Induces Non-alcoholic Steatohepatitis in an Animal Model
Endoplasmic reticulum (ER) stress refers to a condition of accumulation of unfolded or misfolded proteins in the ER lumen, which is known to activate an intracellular stress signaling termed Unfolded Protein Response (UPR). A number of pharmacologic reagents or pathophysiologic stimuli can induce ER...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3334434/ https://ncbi.nlm.nih.gov/pubmed/22414386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2012.02.017 |
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