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Decreased expression of the glial water channel aquaporin-4 in the intrahippocampal kainic acid model of epileptogenesis

Recent evidence suggests that astrocytes may be a potential new target for the treatment of epilepsy. The glial water channel aquaporin-4 (AQP4) is expressed in astrocytes, and along with the inwardly-rectifying K(+) channel K(ir)4.1 is thought to underlie the reuptake of H(2)O and K(+) into glial c...

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Hlavní autoři: Lee, Darrin J., Hsu, Mike S., Seldin, Marcus M., Arellano, Janetta L., Binder, Devin K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334411/
https://ncbi.nlm.nih.gov/pubmed/22361023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2012.02.002
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