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Tumors skew endothelial cells to disrupt NK cell, T-cell and macrophage functions

INTRODUCTION: Patients and mice with solid tumors, such as Lewis lung carcinoma (LLC), have defects in functions of immune effector cells. Endothelial cells, a component of the tumor vasculature, are potential regulators of immune cell functions. Therefore, these studies examined the impact of expos...

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Autori principali: Mulligan, Jennifer K., Lathers, Deanne M. R., Young, M. Rita I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3333838/
https://ncbi.nlm.nih.gov/pubmed/18058097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-007-0425-x
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