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Higher FKBP5, COMT, CHRNA5, and CRHR1 allele burdens are associated with PTSD and interact with trauma exposure: implications for neuropsychiatric research and treatment

OBJECTIVE: The study aim was to assess the cumulative burden of polymorphisms located within four genetic loci previously associated with posttraumatic stress disorder (PTSD) among outpatients at risk for PTSD. METHODS: Diagnostic interviews were completed and DNA samples collected among 412 pain pa...

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Autori principali: Boscarino, Joseph A, Erlich, Porat M, Hoffman, Stuart N, Zhang, Xiaopeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3333786/
https://ncbi.nlm.nih.gov/pubmed/22536069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S29508
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