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Assessing the utility of gene co-expression stability in combination with correlation in the analysis of protein-protein interaction networks

BACKGROUND: Gene co-expression, in the form of a correlation coefficient, has been valuable in the analysis, classification and prediction of protein-protein interactions. However, it is susceptible to bias from a few samples having a large effect on the correlation coefficient. Gene co-expression s...

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Autores principales: Patil, Ashwini, Nakai, Kenta, Kinoshita, Kengo
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3333178/
https://ncbi.nlm.nih.gov/pubmed/22369639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-S3-S19
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