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Metalloproteases of human articular cartilage that digest cartilage proteoglycan at neutral and acid pH.

Extracts of human articular cartilage contain proteases capable of degrading the proteoglycan component of cartilage matrix at neutral and acid pH. These enzymes have been partially purified by ion exchange chromotography and characterized by disc electrophoresis, inhibition patterns, and action of...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Sapolsky, A I, Keiser, H, Howell, D S, Woessner, J F
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1976
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333267/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9425/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108526
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