Lead poisoning: association with hemolytic anemia, basophilic stippling, erythrocyte pyrimidine 5'-nucleotidase deficiency, and intraerythrocytic accumulation of pyrimidines.

Lead intoxication is accompanied by an acquired deficiency of erythrocyte pryimidine-specific, 5'-nucleotidase. Genetically determined deficiency of this enzyme is associated with chronic hemolysis, marked basophilic stippling of erythrocytes on stained blood films, and unique intraerythrocytic...

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Publicat a:J Clin Invest
Autors principals: Valentine, W N, Paglia, D E, Fink, K, Madokoro, G
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 1976
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/965496/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108545
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