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Postmortem Genetic Testing for Conventional Autopsy–Negative Sudden Unexplained Death: An Evaluation of Different DNA Extraction Protocols and the Feasibility of Mutational Analysis From Archival Paraffin-Embedded Heart Tissue
One third of autopsy-negative sudden unexplained deaths (SUDs) can be attributed to a cardiac channelopathy. Typically, paraffin-embedded tissue (PET) is the only source of DNA available for genetic analyses. We examined different DNA extraction procedures, involving 2 deparaffinization methods, 2 d...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3332542/ https://ncbi.nlm.nih.gov/pubmed/18285261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1309/VLA7TT9EQ05FFVN4 |
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