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Susceptibility of HIV Type 2 Primary Isolates to CCR5 and CXCR4 Monoclonal Antibodies, Ligands, and Small Molecule Inhibitors

Human immunodeficiency virus (HIV) entry into susceptible cells involves the interaction between viral envelope glycoproteins with CD4 and a chemokine receptor (coreceptor), namely CCR5 and CXCR4. This interaction has been studied to enable the discovery of a new class of antiretroviral drugs that t...

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Podrobná bibliografie
Hlavní autoři: Espirito-Santo, Maria, Santos-Costa, Quirina, Calado, Marta, Dorr, Patrick, Azevedo-Pereira, J. Miguel
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3332526/
https://ncbi.nlm.nih.gov/pubmed/21902586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2011.0124
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