Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents

Fungal, bacterial, and cancer cells can develop resistance against antifungal, antibacterial, or anticancer agents. Mechanisms of resistance are complex and often multifactorial. Mechanisms include: (1) Activation of ATP-binding cassette (ABC) transporters, such as P-gp, which pump out lipophilic co...

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Bibliografiske detaljer
Main Authors: Wink, Michael, Ashour, Mohamed L., El-Readi, Mahmoud Zaki
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Research Foundation 2012
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3332394/
https://ncbi.nlm.nih.gov/pubmed/22536197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2012.00130
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