Effects of single therapeutic doses of promethazine, fexofenadine and olopatadine on psychomotor function and histamine-induced wheal- and flare-responses: a randomized double-blind, placebo-controlled study in healthy volunteers

Since most first-generation antihistamines have undesirable sedative effects on the central nervous systems (CNS), newer (second-generation) antihistamines have been developed to improve patients’ quality of life. However, there are few reports that directly compare the antihistaminic efficacy and i...

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Main Authors: Kamei, Hiroyuki, Isaji, Ami, Noda, Yukihiro, Ishikawa, Kazuhiro, Senzaki, Koji, Yamada, Kiyofumi, Sugiura, Kazumitsu, Tomita, Yasushi, Nabeshima, Toshitaka
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2011
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3332365/
https://ncbi.nlm.nih.gov/pubmed/22130869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00403-011-1192-2
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