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G9a/GLP Histone Lysine Dimethyltransferase Complex Activity in the Hippocampus and the Entorhinal Cortex Is Required for Gene Activation and Silencing during Memory Consolidation

Learning triggers alterations in gene transcription in brain regions such as the hippocampus and the entorhinal cortex (EC) that are necessary for long-term memory (LTM) formation. Here, we identify an essential role for the G9a/G9a-like protein (GLP) lysine dimethyltransferase complex and the histo...

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Autori principali: Gupta-Agarwal, Swati, Franklin, Aimee V., DeRamus, Thomas, Wheelock, Muriah, Davis, Robin L., McMahon, Lori L., Lubin, Farah D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3332335/
https://ncbi.nlm.nih.gov/pubmed/22514307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0147-12.2012
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