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Chronic helminth infection reduces basophil responsiveness in an IL-10-dependent manner(1)

Basophils play a key role in the development and effector phases of type 2 immune responses in both allergic diseases and helminth infections. This study shows that basophils become less responsive to IgE-mediated stimulation when mice are chronically infected with Litomosoides sigmodontis, a filari...

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Main Authors: Larson, David, Hübner, Marc P., Torrero, Marina N., Morris, Christopher P., Brankin, Amy, Swierczewski, Brett E., Davies, Stephen J., Vonakis, Becky, Mitre, Edward
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331970/
https://ncbi.nlm.nih.gov/pubmed/22461700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101859
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