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SIRPα and FHOD1 are unique markers of littoral cells, a recently evolved major cell population of red pulp of human spleen

Asplenic individuals are compromised not only in their ability to destroy infectious agents, but are at increased risk of death from autoimmune disease, certain tumors, and ischemic heart disease. Enhanced mortality is attributed to lack of phagocytes sequestered in spleen that efficiently engulf an...

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Bibliographic Details
Main Authors: Ogembo, Javier Gordon, Milner, Danny A., Mansfield, Keith G., Rodig, Scott J., Murphy, George F., Kutok, Jeffery L., Pinkus, Geraldine S., Fingeroth, Joyce D.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331893/
https://ncbi.nlm.nih.gov/pubmed/22490440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103086
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