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Performance of penalized maximum likelihood in estimation of genetic covariances matrices

BACKGROUND: Estimation of genetic covariance matrices for multivariate problems comprising more than a few traits is inherently problematic, since sampling variation increases dramatically with the number of traits. This paper investigates the efficacy of regularized estimation of covariance compone...

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Autore principale: Meyer, Karin
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331854/
https://ncbi.nlm.nih.gov/pubmed/22117894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1297-9686-43-39
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