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Rate and breadth of protein evolution are only weakly correlated

BACKGROUND: Evolution at a protein site can be characterized from two different perspectives, by its rate and by the breadth of the set of acceptable amino acids. RESULTS: There is a weak positive correlation between rates and breadths of evolution, both across individual amino acid sites and across...

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Autori principali: Naumenko, Sergey A, Kondrashov, Alexey S
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331848/
https://ncbi.nlm.nih.gov/pubmed/22336199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-7-8
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