Pooled analysis of cardiac safety in patients with cancer treated with pertuzumab

BACKGROUND: Pertuzumab, a human epidermal growth factor receptor (HER) 2 dimerization inhibitor, has demonstrated promising efficacy in combination with trastuzumab in patients with metastatic breast cancer. As HER signaling pathways are not only involved in oncogenesis, but also in myocardial homeo...

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Bibliographic Details
Main Authors: Lenihan, D., Suter, T., Brammer, M., Neate, C., Ross, G., Baselga, J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331733/
https://ncbi.nlm.nih.gov/pubmed/21665955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdr294
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