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Molecular Basis for the Regulation of Angiogenesis by Thrombospondin-1 and -2
Thrombospondins TSP-1 and TSP-2 are potent endogenous inhibitors of angiogenesis. They inhibit angiogenesis through direct effects on endothelial cell migration, proliferation, survival, and apoptosis and by antagonizing the activity of VEGF. Several of the membrane receptor systems and signal trans...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3331684/ https://ncbi.nlm.nih.gov/pubmed/22553494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a006627 |
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