Loss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1

AIMS: While a wealth of data has uncovered distinct microRNA (miR) expression alterations in hypertrophic and ischaemic/reperfused (I/R) hearts, little is known about miR regulation and response to ischaemic preconditioning (IPC). METHODS AND RESULTS: We analysed miRs in murine hearts preconditioned...

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Detalhes bibliográficos
Main Authors: Wang, Xiaohong, Zhu, Hongyan, Zhang, Xiaowei, Liu, Yong, Chen, Jing, Medvedovic, Mario, Li, Hongliang, Weiss, Mitchell J., Ren, Xiaoping, Fan, Guo-Chang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Original Articles: Spotlight on Reducing Myocardial Ischaemia/Reperfusion Injury
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331614/
https://ncbi.nlm.nih.gov/pubmed/22354898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs096
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