Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a complex disease with poorly understood etiology. Previously, we reported upregulation of matrix metalloproteinase 7 (MMP7) in both lung and peripheral blood of IPF patients. Here we report evidence for genetic correlation of plasma levels and promoter polymor...

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Main Authors: Richards, Thomas J., Park, Chunghyun, Chen, Yiliang, Gibson, Kevin F., Peter Di, Y., Pardo, Annie, Watkins, Simon C., Choi, Augustine M. K., Selman, Moises, Pilewski, Joseph, Kaminski, Naftali, Zhang, Yingze
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3331579/
https://ncbi.nlm.nih.gov/pubmed/22268124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00319.2011
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