Williams trait. Human kininogen deficiency with diminished levels of plasminogen proactivator and prekallikrein associated with abnormalities of the Hageman factor-dependent pathways.

An asymptomatic woman (Ms. Williams) was found to have a severe abnormality in the surface-activated intrinsic coagulation, fibrinolytic, and kinin-generating pathways. Assays for known coagulation factors were nromal while Fletcher factor (pre-kallikrein) was 45%, insufficient to account for the ob...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Colman, R W, Bagdasarian, A, Talamo, R C, Scott, C F, Seavey, M, Guimaraes, J A, Pierce, J V, Kaplan, A P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1975
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333144/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1202089/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108247
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