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Is aromatization of testosterone to estradiol required for inhibition of luteinizing hormone secretion in men?

A variety of studies in man and animals demonstrate that testosterone (T) is aromatized to estradiol (E) in the hypothalamus and limbic system. These observations suggested the possibility that conversion to E is an absolute requirement for the biologic activity of T on the hypothalamic-pituitary ax...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autore principale: Santen, R J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1975
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333134/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1104659/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108237
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