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ERK acts in parallel to PKCδ to mediate the connexin43-dependent potentiation of Runx2 activity by FGF2 in MC3T3 osteoblasts

The gap junction protein, connexin43 (Cx43), plays an important role in skeletal biology. Previously, we have shown that Cx43 can enhance the signaling and transcriptional response to fibroblast growth factor 2 (FGF2) in osteoblasts by increasing protein kinase C-δ (PKCδ) activation to affect Runx2...

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Bibliographische Detailangaben
Hauptverfasser: Niger, Corinne, Buo, Atum M., Hebert, Carla, Duggan, Brian T., Williams, Mark S., Stains, Joseph P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330735/
https://ncbi.nlm.nih.gov/pubmed/22277757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00262.2011
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