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Depolymerization of cortical actin inhibits UT-A1 urea transporter endocytosis but promotes forskolin-stimulated membrane trafficking

The cytoskeleton participates in many aspects of transporter protein regulation. In this study, by using yeast two-hybrid screening, we identified the cytoskeletal protein actin as a binding partner with the UT-A1 urea transporter. This suggests that actin plays a role in regulating UT-A1 activity....

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Detalhes bibliográficos
Main Authors: Xu, Gang, Su, Hua, Carter, Conner B., Fröhlich, Otto, Chen, Guangping
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330733/
https://ncbi.nlm.nih.gov/pubmed/22262062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00440.2011
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