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Endothelial cells express a unique transcriptional profile under very high wall shear stress known to induce expansive arterial remodeling

Chronic high flow can induce arterial remodeling, and this effect is mediated by endothelial cells (ECs) responding to wall shear stress (WSS). To assess how WSS above physiological normal levels affects ECs, we used DNA microarrays to profile EC gene expression under various flow conditions. Cultur...

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Detalhes bibliográficos
Main Authors: Dolan, Jennifer M., Sim, Fraser J., Meng, Hui, Kolega, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330730/
https://ncbi.nlm.nih.gov/pubmed/22173868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00369.2011
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