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Endothelial cells express a unique transcriptional profile under very high wall shear stress known to induce expansive arterial remodeling

Chronic high flow can induce arterial remodeling, and this effect is mediated by endothelial cells (ECs) responding to wall shear stress (WSS). To assess how WSS above physiological normal levels affects ECs, we used DNA microarrays to profile EC gene expression under various flow conditions. Cultur...

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Bibliografiske detaljer
Main Authors: Dolan, Jennifer M., Sim, Fraser J., Meng, Hui, Kolega, John
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330730/
https://ncbi.nlm.nih.gov/pubmed/22173868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00369.2011
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