Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes

To discover hypothalamic genes that might play a role in regulating energy balance, we carried out a microarray screen for genes induced by a 48-h fast in male C57Bl/6J mouse hypothalamus. One such gene was Fkbp51 (FK506 binding protein 5; Locus NP_034350). The product of this gene is of interest be...

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Auteurs principaux: Yang, Linda, Isoda, Fumiko, Yen, Kelvin, Kleopoulos, Steven P., Janssen, William, Fan, Xiaoning, Mastaitis, Jason, Dunn-Meynell, Ambrose, Levin, Barry, McCrimmon, Rory, Sherwin, Robert, Musatov, Sergei, Mobbs, Charles V.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2012
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330722/
https://ncbi.nlm.nih.gov/pubmed/22318949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00474.2011
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