25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages

The nuclear receptor peroxisome proliferator-activated receptors (PPARs) are important in regulating lipid metabolism and inflammatory responses in macrophages. Activation of PPARγ represses key inflammatory response gene expressions. Recently, we identified a new cholesterol metabolite, 25-hydroxyc...

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Bibliografiske detaljer
Main Authors: Xu, Leyuan, Shen, Shanwei, Ma, Yongjie, Kim, Jin Koung, Rodriguez-Agudo, Daniel, Heuman, Douglas M., Hylemon, Phillip B., Pandak, William M., Ren, Shunlin
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2012
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3330710/
https://ncbi.nlm.nih.gov/pubmed/22275753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00337.2011
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