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Reversal of Cyclic AMP-Mediated Intestinal Secretion by Ethacrynic Acid

Ethacrynic acid (EA) has been reported to reduce cholera toxin-induced intestinal fluid secretion in the intact animal. We explored the nature of this inhibition in vitro by measuring unidirectional, transmural fluxes of (22)Na and (36)Cl across isolated rabbit ileal mucosa. Under control conditions...

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Vydáno v:J Clin Invest
Hlavní autoři: Al-Awqati, Qais, Field, Michael, Greenough, William B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1974
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC333048/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4359936/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107606
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