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A cell-based phenotypic assay to identify cardioprotective agents

RATIONALE: Tissue ischemia/reperfusion (IR) injury underlies several leading causes of death such as heart-attack and stroke. The lack of clinical therapies for IR injury may be partly due to the difficulty of adapting IR injury models to high-throughput screening (HTS). OBJECTIVE: To develop a mode...

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Autori principali: Guo, Stephanie, Olm-Shipman, Adam, Walters, Andrew, Urciuoli, William R., Devito, Stefanie, Nadtochiy, Sergiy M., Wojtovich, Andrew P., Brookes, Paul S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329894/
https://ncbi.nlm.nih.gov/pubmed/22394516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.263715
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