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An Effect of Dexamethasone on Adenosine 3′,5′ -Monophosphate Content and Adenosine 3′,5′ -Monophosphate Phosphodiesterase Activity of Cultured Hepatoma Cells

The effect of dexamethasone on adenosine 3′,5′-monophosphate (cAMP) phosphodiesterase activity in cultured HTC hepatoma cells was investigated. Homogenates of these cells contain phosphodiesterase activity with two apparent Michaelis constants for cAMP (2-5 μm and 50 μm). At all substrate concentrat...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Manganiello, Vincent, Vaughan, Martha
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1972
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC332977/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4341439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI107096
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