Histone deacetylase inhibitors, valproic acid and trichostatin-A induce apoptosis and affect acetylation status of p53 in ERG-positive prostate cancer cells

An ETS family member, ETS Related Gene (ERG) is involved in the Ewing family of tumors as well as leukemias. Rearrangement of the ERG gene with the TMPRSS2 gene has been identified in the majority of prostate cancer patients. Additionally, overexpression of ERG is associated with un- favorable progn...

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Autori principali: FORTSON, WENDELL S., KAYARTHODI, SHUBHALAXMI, FUJIMURA, YASUO, XU, HUALI, MATTHEWS, ROLAND, GRIZZLE, WILLIAM E., RAO, VEENA N., BHAT, GANAPATHY K., REDDY, E. SHYAM P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329756/
https://ncbi.nlm.nih.gov/pubmed/21519790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2011.1014
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