Feline Neural Progenitor Cells II: Use of Novel Plasmid Vector and Hybrid Promoter to Drive Expression of Glial Cell Line-Derived Neurotrophic Factor Transgene

Sustained transgene expression is required for the success of cell transplant-based gene therapy. Most widely used are lentiviral-based vectors which integrate into the host genome and thereby maintain sustained transgene expression. This requires integration into the nuclear genome, and potential r...

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Autores principales: You, X. Joann, Yang, Jing, Gu, Ping, Liew, Chee Gee, Klassen, Henry J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329736/
https://ncbi.nlm.nih.gov/pubmed/22550512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/604982
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