Establishment of a leptospirosis model in guinea pigs using an epicutaneous inoculations route

BACKGROUND: Leptospires are presumed to enter their host via small abrasions or breaches of the skin. The intraperitoneal route, although commonly used in guinea pig and hamster models of leptospirosis, does not reflect conditions encountered during natural infection. The aim of this study is to dev...

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Autores principales: Zhang, Yan, Lou, Xiao-Li, Yang, Hong-Liang, Guo, Xiao-Kui, Zhang, Xiang-Yan, He, Ping, Jiang, Xu-Cheng
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329641/
https://ncbi.nlm.nih.gov/pubmed/22273178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-12-20
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