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Stimulus-responsive Controlled Release System by Covalent Immobilization of an Enzyme into Mesoporous Silica Nanoparticles

Mesoporous silica nanoparticles (MSN) have emerged as an attractive class of drug delivery carriers for therapeutic agents. Herein, we explored the covalent immobilization of proteins into MSN to generate a stimulus-responsive controlled release system. First, MSN were functionalized with thiol grou...

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Autores principales: Méndez, Jessica, Monteagudo, Alina, Griebenow, Kai
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329583/
https://ncbi.nlm.nih.gov/pubmed/22375899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200301a
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