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Myosin Light Chain Kinase Mediates Intestinal Barrier Disruption following Burn Injury

BACKGROUND: Severe burn injury results in the loss of intestinal barrier function, however, the underlying mechanism remains unclear. Myosin light chain (MLC) phosphorylation mediated by MLC kinase (MLCK) is critical to the pathophysiological regulation of intestinal barrier function. We hypothesize...

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Detalhes bibliográficos
Main Authors: Chen, Chuanli, Wang, Pei, Su, Qin, Wang, Shiliang, Wang, Fengjun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329538/
https://ncbi.nlm.nih.gov/pubmed/22529961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034946
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